Publicaciones del Grupo de Investigación del LQO - IQB

145) Structural relationships in the solid state of the anti-chagas agent (E)-phenylethenylbenzofuroxan
2009
Mol. Divers., 2009, en prensa
Martins FT, Ayala AP, Porcal W, Cerecetto H, González M, Ellena J.

144) Anti-trypanosomatid benzofuroxans and deoxygenated analogues: Synthesis using polymer-supported triphenylphosphine, biological evaluation and mechanism of action studies
2009
Eur. J. Med. Chem., 2009, en prensa
Diego Castro, Lucia Boiani, Diego Benitez, Paola Hernández, Alicia Merlino, Carmen Gil, Claudio Olea-Azar, Mercedes González, Hugo Cerecetto, Williams Porcal

143) Effect of ruthenium complexation on trypanocidal activity of 5-nitrofuryl containing thiosemicarbazones
2009
Eur. J. Med. Chem., 2009, en prensa
Mariana Pagano, Bruno Demoro, Jeanette Toloza, Lucía Boiani, Mercedes González,Hugo Cerecetto, Claudio Olea-Azar, Ester Norambuena, Dinorah Gambino, Lucía Otero

142) o-Nitroanilines as major metabolic products of anti-Trypanosoma cruzi 5-phenylethenylbenzofuroxans in microsomal and cytosolic fractions of rat hepatocytes and in whole parasitic cells
2009
Xenobiotica, 2009,39, 236-248
Boiani M, Merlino A, Gerpe A, Porcal W, Croce F, Depaula S, Rodríguez MA, Cerecetto H, González M.Cerecetto H, González M

141) Heterocyclic-2-carboxylic acid (3-cyano-1,4-di-N-oxidequinoxalin-2-yl)amide derivatives as hits for the development of neglected disease drugs
2009
Molecules, 2009, 14, 2256-2272
Ancizu S, Moreno E, Torres E, Burguete A, Pérez-Silanes S, Benítez D, Villar R, Solano B, Marín A, Aldana I, Cerecetto H, González M, Monge A.

140) Interaction studies between human alpha-tocopherol transfer protein and nitric oxide donor tocopherol analogues with LDL-protective activity
2009
Bioorg. Med. Chem., 2009, 17, 8143-8148
Gloria V. López, Luis E. Gómez, Nuria Campillo, Juan A. Páez, Kaleigh Giles, Jeffrey Atkinson, Mercedes González, Homero Rubbo, Hugo Cerecetto

139) Second generation of 2H-benzimidazole 1,3-dioxide derivatives as anti-trypanosomatid agents: Synthesis, biological evaluation, and mode of action studies
2009
Eur. J. Med. Chem., 2009, 44, 4426-4433
Mariana Boiani, Lucía Boiani, Alicia Merlino, Paola Hernández, Agustina Chidichimo, Juan J. Cazzulo, Hugo Cerecetto, Mercedes González

138) 5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene
2009
Bioorg. Med. Chem., 2009, 17, 7500-7509
Alejandra Gerpe, Guzmán Álvarez, Diego Benítez, Lucía Boiani, Martín Quiroga, Paola Hernández, Maximiliano Sortino, Susana Zacchino, Mercedes González, Hugo Cerecetto

137) Platinum-based complexes of bioactive 3-(5-nitrofuryl)acroleine thiosemicarbazones showing anti-Trypanosoma cruzi activity
2009
J. Inorg. Biochem., 2009, 103, 411-418
Marisol Vieites, Lucía Otero, Diego Santos, Claudio Olea-Azar, Ester Norambuena, Gabriela Aguirre, Hugo Cerecetto, Mercedes González, Ulrike Kemmerling, Antonio Morello, Juan Diego Maya, Dinorah Gambino

136) New potent 5-nitroindazole derivatives as inhibitors of Trypanosoma cruzi growth: Synthesis, biological evaluation, and mechanism of action studies
2009
Bioorg. Med. Chem., 2009, 17, 8186-8196
Jorge Rodríguez, Vicente J. Arán, Lucía Boiani, Claudio Olea-Azar, María Laura Lavaggi, Mercedes González, Hugo Cerecetto, Juan Diego Maya, Catalina Carrasco-Pozo, Hernán Speisky Cosoy

135) Cytotoxic, mutagenic and genotoxic effects of new anti-T. cruzi 5-phenylethenylbenzofuroxans. Contribution of phase I metabolites on the mutagenicity induction
2009
Toxicol. Letters, 2009, 190, 140-149
Mauricio Cabrera, María Laura Lavaggi, Paola Hernández, Alicia Merlino, Alejandra Gerpe, Williams Porcal, Mariana Boiani, Ana Ferreira, Antonio Monge, Adela López de Cerain, Mercedes González, Hugo Cerecetto

134) Cytotoxic palladium complexes of bioreductive quinoxaline N1,N4-dioxide prodrugs
2009
Bioorg. Med. Chem., 2009, 17, 1623-1629
Carolina Urquiola, Marisol Vieites, María H. Torre, Mauricio Cabrera, María Laura Lavaggi, Hugo Cerecetto, Mercedes González, Adela López de Cerain, Antonio Monge, Pablo Smircich, Beatriz Garat, Dinorah Gambino

133) 5-Nitro-2-furyl derivative actives against Trypanosoma cruzi: Preliminary in vivo studies
2009
Eur. J. Med. Chem., 2009, 44, 3909-3914
Eliana Cabrera, Mariana González Murguiondo, Marelina González Arias, Carolina Arredondo, Cristina Pintos, Gabriela Aguirre, Marcelo Fernández, Yester Basmadjián, Raquel Rosa, José Pedro Pacheco, Stella Raymondo, Rossanna Di Maio, Mercedes González, Hugo Cerecetto

132) Study of 5-nitroindazoles' anti-Trypanosoma cruzi mode of action: Electrochemical behaviour and ESR spectroscopic studies
2009
Eur. J. Med. Chem., 2009, 44, 1545-1553
Jorge Rodríguez, Alejandra Gerpe, Gabriela Aguirre, Ulrike Kemmerling, Oscar E. Piro, Vicente J. Arán, Juan Diego Maya, Claudio Olea-Azar, Mercedes González, Hugo Cerecetto

131) Review: Anti-T. cruzi agents: our experience in the evaluation of more than five hundred compounds
2008
Mini Rev. Med. Chem., 2008, 8, 1355-1383
Hugo Cerecetto, Mercedes González

130) New potent imidazoisoquinolinone derivatives as anti-Trypanosoma cruzi agents: Biological evaluation and structure–activity relationships
2009
Bioorg. Med. Chem., 2008, 17, 1437-1444
Mariela Bollini, Juan José Casal, Diego E. Alvarez, Lucía Boiani, Mercedes González, Hugo Cerecetto, Ana María Bruno

129) Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates
2009
Bioorg. Med. Chem., 2008, 17, 641-652
Nelilma C. Romeiro, Gabriela Aguirre, Paola Hernández, Mercedes González, Hugo Cerecetto, Ignacio Aldana, Silvia Pérez-Silanes, Antonio Monge, Eliezer J. Barreiro, Lídia M. Lima

128) Furoxan-, alkylnitrate-derivatives and related compounds as anti-trypanosomatid agents: Mechanism of action studies
2008
Bioorg. Med. Chem., 2008, 16, 7900-7907
Lucía Boiani, Gabriela Aguirre, Mercedes González, Hugo Cerecetto, Agustina Chidichimo, Juan J. Cazzulo, Massimo Bertinaria, Stefano Guglielmo

127) In vitro and In vivo Antitrypanosomatid Activity of 5-Nitroindazoles
2008
Eur. J. Med. Chem., 2008, 44, 1034-1040
Lucia Boiani, Alejandra Gerpe, Vicente J. Arán, Susana Torres de Ortiz, Elva Serna, Ninfa Vera de Bilbao, Luis Sanabria, Gloria Yaluff, Héctor Nakayama, Antonieta Rojas de Arias, Juan Diego Maya, J. Antonio Morello, Hugo Cerecetto, Mercedes Gonzalez.

126) Differential enzymatic reductions governing the differential hypoxia-selective cytotoxicities of phenazine 5,10-dioxides
2008
Chem. Res. Toxicol., 2008, 21, 1900-1906
Lavaggi ML, Cabrera M, González M, Cerecetto H.

125) A convenient route to primary (Z)-allyl amines and homologues
2008
Synth. Comm., 2008, en prensa
Gerpe A, Bollini M, González M, Cerecetto H.

124) Antitumoral effect of phenazine N5,N10-dioxide derivatives on Caco-2 cells
2008
Chem. Res. Toxicol., 2008, 21, 1578-1585
Pachón OG, Azqueta A, Lavaggi ML, López de Cerain A, Creppy E, Collins A, Cerecetto H, González M, Centelles JJ, Cascante M.

123) New trypanocidal hybrid compounds from the association of hydrazones moieties and benzofuroxan heterocycle
2008
Bioorg. Med. Chem., 2008, 16, 6995-7004
Porcal W, Hernández P, Boiani L, Boiani M, Ferreira A, Chidichimo A, Cazzulo JJ, Olea-Azar C, González M, Cerecetto H.

122) Pyrimido[1,2-a]quinoxaline 6-oxide and phenazine 5,10-dioxide derivatives and related compounds as growth inhibitors of Trypanosoma cruzi
2008
Eur. J. Med. Chem., 2008, 43, 1737-1741
Lavaggi ML, Aguirre G, Boiani L, Orelli L, García B, Cerecetto H, González M.

121) Development of a HPLC method for the determination of antichagasic phenylethenylbenzofuroxans and its major synthetic secondary products in the chemical production processes
2008
J. Pharm. Biomed. Anal., 2008, 47, 88-94
Gerpe A, Merlino A, Boiani M, Porcal W, Fagiolino P, González M, Cerecetto H.

120) In vivo studies of 5-arylethenylbenzofuroxans in acute murine models of Chagas' disease
2008
Eur. J. Med. Chem., 2008, 43, 2229-2237
Boiani L, Davies C, Arredondo C, Porcal W, Merlino A, Gerpe A, Boiani M, Pacheco JP, Basombrío MA, Cerecetto H, González M.

119) Platinum(II) metal complexes as potential anti-Trypanosoma cruzi agents
2008
J. Inorg. Biochem., 2008, 102, 1033-1043
Vieites M, Otero L, Santos D, Toloza J, Figueroa R, Norambuena E, Olea-Azar C, Aguirre G, Cerecetto H, González M, Morello A, Maya JD, Garat B, Gambino D

118) Insight into the bioreductive mode of action of antitrypanosomal 5-nitrofuryl containing thiosemicarbazones
2008
Med. Chem., 2008, 4, 11-17
Otero L, Maya JD, Morello A, Rigol C, Barriga G, Rodríguez J, Folch C, Norambuena E, González M, Azar CO, Cerecetto H, Gambino D

117) Potent in vitro anti-Trypanosoma cruzi activity of pyridine-2-thiol N-oxide metal complexes having an inhibitory effect on parasite-specific fumarate reductase
2008
J. Biol. Inorg. Chem., 2008, 13, 723-735
Vieites, M.; Smircich, P.; Parajón-Costa, B.; Rodríguez, J.; Galaz, V.; Olea-Azar, C.; Otero, L.; Aguirre, G.; Cerecetto, H.; González, M.; Gómez-Barrio, A.; Garat, B.; Gambino, D.

116) Arylethenylbenzofuroxan derivatives as drugs for Chagas disease: Multigram batch synthesis using a Wittig-Boden process
2008
Org. Process Res. Dev., 2008, 12, 156-162
Porcal, W.; Merlino, A.; Boiani, M.; Gerpe, A.; González, M.; Cerecetto, H.

115) Imidazolidines as new anti-Trypanosoma cruzi agents: Biological evaluation and structure-activity relationships
2008
Bioorg. Med. Chem., 2008, 16, 2226-2234
Caterina MC, Perillo IA, Boiani L, Pezaroglo H, Cerecetto H, González M, Salerno A.

114) Modeling anti-Trypanosoma cruzi activity of N-oxide containing heterocycles
2008
J. Chem. Inf. Model., 2008, 48, 213-219
Boiani M, Cerecetto H, Gonzalez M, Gasteiger J.

113) Heteroallyl-containing 5-nitrofuranes as new anti-Trypanosoma cruzi agents with a dual mechanism of action
2008
Bioorg. Med. Chem., 2008, 16, 569-577
Gerpe, A.; Odreman-Nuñez, I.; Draper, P.; Boiani, L.; Urbina, J.A.; González, M.; Cerecetto, H.

112) Non-ATP competitive glycogen synthase kinase 3beta (GSK-3beta) inhibitors: study of structural requirements for thiadiazolidinone derivatives
2008
Bioorg. Med. Chem., 2008, 16, 495-510
Castro A, Encinas A, Gil C, Bräse S, Porcal W, Pérez C, Moreno FJ, Martínez A

111) ESR, electrochemical and reactivity studies of antitrypanosomal palladium thiosemicarbazone complexes
2008
Spectrochim. Acta A Mol. Biolmol. Spectrosc., 2008, 70, 519-523
Otero, L.; Folch, C.; Barriga, G.; Rigol, C.; Opazo, L.; Vieites, M.; Gambino, D.; Cerecetto, H.; Norambuena, E.; Olea-Azar, C.

110) Comparative spectroscopic and electrochemical study of nitroindazoles: 3-Alcoxy, 3-hydroxy and 3-oxo derivatives
2008
Spectrochim. Acta A Mol. Biolmol. Spectrosc., 2008, 70, 557-563
Rodríguez, J.; Olea-Azar, C.; Barriga, G.; Folch, C.; Gerpe, A.; Cerecetto, H.; González, M.

109) New copper-based complexes with quinoxaline N(1),N(4)-dioxide derivatives, potential antitumoral agents
2008
J. Inorg. Biochem., 2008, 102, 119-126
Urquiola, C.; Gambino, D.; Cabrera, M.; Lavaggi, M.L.; Cerecetto, H.; González, M.; López de Ceráin, A.; Monge, A.; Costa-Filho, A.J.; Torre, M.H.

108) 4-Nitroacetophenone-derived thiosemicarbazones and their copper(II) complexes with significant in vitro anti-trypanosomal activity
2008
Eur. J. Med. Chem., 2008, 939-948
Pérez-Rebolledo, A.; Teixeira, L.R.; Batista, A.A.; Mangrich, A.S.; Aguirre, G.; Cerecetto, H.; González, M.; Hernández, P.; Ferreira, A.M.; Speziali, N.L.; Beraldo, H.

107) Preparation and characterization of technetium and rhenium tricarbonyl complexes bearing the 4-nitrobenzyl moiety as potential bioreductive diagnostic radiopharmaceuticals. In vitro and in vivo studies
2008
Eur. J. Med. Chem., 2008, 43, 741-748
Giglio, J.; Patsis, G.; Pirmettis, I.; Papadopoulos, M.; Raptopoulou, C.; Pelecanou, M.; León, E.;
González, M.; Cerecetto, H.; Rey, A.

106) In vivo anti-Chagas vinylthio-, vinylsulfinyl- and vinylsulfonyl-benzofuroxan derivatives
2007
J. Med. Chem., 2007, 50, 6004-6015
Porcal, W.; Hernández, P.; Boiani, M.; Aguirre, G.; Boiani, L.; Chidichimo, A.; Cazzulo, J.J.; Campillo, N.E.; Páez, J.A.; Castro, A.; Krauth-Siegel, R.L.; Davies, C.; Basombrío, M.A.; González, M.; Cerecetto, H.

105) Interaction energies of nitrofurans with trypanothione reductase and glutathione reductase studied by molecular docking
2007
J. Mol. Struct. THEOCHEM, 2007, 818, 7-22
Iribarne, F.; González, M.; Cerecetto, H.; Aguilera, S.; Tapia, O.; Paulino, M.

104) Second generation of alpha-tocopherol analogs-nitric oxide donors: Synthesis, physicochemical, and biological characterization
2007
Bioorg. Med. Chem., 2007, 15, 6262-72
Lopez, G.V.; Blanco, F.;
Hernández, P.; Ferreira, A.; Piro, O.E.; Batthyany, C.; González, M..; Rubbo, H.; Cerecetto, H.

103) Amphiphilic NO-donor antioxidants
2007
ChemMedChem, 2007, 2, 234-240
Chegaev, K.; Lazzarato, L.; Rolando, B.; Marini, E.; Lopez, V.; Bertinaria, M.; Di Stilo, A.; Fruttero, R.; Gasco, A.

102) Structure of indazole N1-oxide derivatives studied by X-ray, 3 theoretical methods, 1H, 13C, 15N NMR and EI/MS
2007
J. Mol. Struct., 2007, 871, 98-107
A Gerpe, OE Piro, H Cerecetto, M González

101) Synthetic Chalcones, Flavanones and Flavones as Antitumoral Agents: Biological Evaluation and Structure-Activity Relationships
2007
Bioorg. Med. Chem., 2007, 15, 3356-67.

M Cabrera, M Simoens, G Falchi, ML Lavaggi
, OE. Piro, EE Castellano, A Vidal, A Azqueta, A Monge, A López de Ceráin, G Sagrera, G Seoane, H Cerecetto, M González

100) Synthesis, Isomer Characterization, and Anti-Inflammatory Properties of Nitroarachidonate
2007

Biochem., 2007, 46, 4645-53.

A Trostchansky, JM. Souza, A Ferreira, M Ferrari, F Blanco, M Trujillo, D Castro, H Cerecetto, PR Baker, VB O’Donnell, H Rubbo

99) Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: Synthesis, biological evaluation, and structure-activity relationships.
2007
Bioorg. Med. Chem., 2007, 15, 2768-81.

Porcal W, Hernandez P, Aguirre G, Boiani L, Boiani M, Merlino A, Ferreira A, Di Maio R, Castro A, Gonzalez M, Cerecetto H.

98) Vibrational spectra of palladium 5-nitrofuryl thiosemicarbazone complexes: Experimental and theoretical study.
2007
Spectrochim. Acta A Mol. Biomol. Spectrosc., 2007, 68, 341-8.

Gambino D, Otero L, Vieites M, Boiani M, Gonzalez M, Baran EJ, Cerecetto H.

97) DNA conformational changes and cleavage by ruthenium (II) nitrofurylsemicarbazone complexes
2007
J. Inorg. Biochem., 2007, 101, 74-9.

L. Otero, P. Smircich, M. Vieites, M. Ciganda, P. Cardoso Severino, H. Terenzi, H. Cerecetto, D. Gambino, B. Garat.

96) Antioxidants derived from vitamin E. An overview
2007
Mini Rev. Med. Chem., 2007, 7. 315-38.
H. Cerecetto, V. López.

95) 2-Benzyl-2-methyl-2H-benzimidazole 1,3-dioxide derivatives: spectroscopic and theoretical study
2007
Spectrochim. Acta Part A, 2007, 67, 540-9.
A. Merlino, M. Boiani, H. Cerecetto, M. González.

94) Solubilization and Release Properties of Dendrimers. Evaluation as Prospective Drug Delivery Systems
2006
Supramol. Chem., 2006, 18, 633–643
L Fernández, M González, H Cerecetto, M Santo, JJ Silber

93) Theoretical study on 5-nitrofuryl thiosemicarbazone radicals electronic properties
2006
J. Mol. Struct. THEOCHEM, 2006, 770, 125-129
Carolina Rigol, Claudio Olea-Azar, Fernando Mendizábal, Rodolfo Briones, Hugo Cerecetto, Mercedes González.

92) Design and Evaluation of "3+1" Mixed Ligand Oxorhenium and Oxotechnetium Complexes Bearing a Nitroaromatic Group with Potential Application in Nuclear Medicine Oncology
2006
Eur. J. Med. Chem., 2006, 41, 1144-1152
J. Giglio, A. Rey, H. Cerecetto, I. Pirmettis, M. Papadopoulos, E. León, A. Monge, A. López de Ceráin, A. Azqueta, M. González, M. Fernández, A. Paolino, A. León.

91) Nitrofurylsemicarbazone Rhenium and Ruthenium Complexes as Antitrypanosomal Agents
2006
Eur. J. Med. Chem., 2006, 41, 1231-9
L. Otero, D. Gambino, G. Aguirre, L. Boiani, H. Cerecetto, M. González, A. Denicola, C. Rigol, C. Olea-Azar, A. Morello, J.D. Maya.

90) One-pot synthesis of benzyltriphenylphosphonium acetates from the corresponding activated benzyl alcohols
2006
ARKIVOC, 2006, xi, 128-136
P. Hernández, A. Merlino, A. Gerpe, W. Porcal, O. E. Piro, M. González, H. Cerecetto.

89) Development of Selective Hypoxic Cytotoxins for Cancer Treatment: an Update
2006
Med. Chem., 2006, 2, 315-327
H. Cerecetto, M. González, M. L. Lavaggi.

88) Improving anti-trypanosomal activity of 3-aminoquinoxaline-2-carbonitrile N1,N4-dioxide derivatives by complexation with vanadium
2006
Bioorg. Med. Chem., 2006, 14, 5503-5592
C. Urquiola, M. Vieites, G. Aguirre, A. Marín, B. Solano, G. Arrambide, P. Noblía, M. L. Lavaggi, M. H. Torre, M. González, A. Monge, D. Gambino, H. Cerecetto.

87) Phenazine 5,10-Dioxide Derivatives as Hypoxic Selective Cytotoxins. Part II. Structure-Activity Relationship Studies
2006
Med. Chem., 2006, 2, 511-521
H. Cerecetto, M. González, M. L. Lavaggi, M. A. Aravena, C. Rigol, C. Olea-Azar, A. Azqueta, A. López de Ceráin, A. Monge, A. M. Bruno.

86) Selective Hypoxia-Cytotoxins Based on Vanadyl Complexes with 3-Aminoquinoxaline-2-Carbonitrile-N1,N4-Dioxide Derivatives
2006
J. Inorg. Biochem., 2006, 100, 1358-67
M. Vieites, P. Noblía, M. H. Torre, H. Cerecetto, M. González, M. L. Lavaggi, A. J. Da Costa Filho, A. López de Cerain, A. Monge, B. Parajón-Costa, D. Gambino.

85) Novel Antitrypanosomal Agents Based on Palladium Nitrofurylthiosemicarbazone Complexes: DNA and Redox Metabolism as Potential Therapeutic Targets
2006
J. Med. Chem., 2006, 49, 3322-3331
L. Otero, M. Vieites, L. Boiani, A. Denicola, C. Rigol, L. Opazo, C. Olea-Azar, J. D. Maya, A. Morello, R. L. Krauth-Siegel, O. E. Piro, E. Castellano, M. González, D. Gambino, H. Cerecetto.

84) Indazole N-Oxide Derivatives as Antiprotozoa Agents. Synthesis, Biological Evaluation and QSAR Studies
2006
Bioorg. Med. Chem., 2006, 14, 3467-3480
A. Gerpe, G. Aguirre, L. Boiani, H. Cerecetto, M. González, C. Olea-Azar, C. Rigol, J.D. Maya, A. Morello, O.E. Piro, C. Ochoa, A. Azqueta, A. López de Ceráin, A. Monge, A. Rojas, G. Yaluff.

83) Synthesis and Characterization of Thiol Containing Furoxan Derivatives as Coligands for the Preparation of Potential Bioreductive
2006
Archiv. Pharmazie, 2006, 339, 59-66
H. Cerecetto, M. González, S. Onetto, M. Risso, A. Rey, J. Giglio, E. León, A. León, P. Pilatti, M. Fernández.

82) Novel vanadyl complexes with quinoxaline N(1),N(4)-dioxide derivatives as potent in vitro insulin-mimetic compounds
2006
J. Inorg. Biochem., 2006, 100, 281-287
P.Noblía, M.Vieites, M.H.Torre, A.J.Costa Filho, H.Cerecetto, M.González, M.L.Lavaggi, Y.Adachi, H.Sakurai, D. Gambino.

81) New Potent 5-Nitrofuryl Derivatives as Inhibitors of Trypanosoma cruzi Growth. 3D-QSAR (CoMFA) Studies
2006
Eur. J. Med. Chem., 2006, 41, 457-466
G. Aguirre, M. Boiani, E. Cabrera, H. Cerecetto, R. Di Maio, M. González, A. Denicola, C. M. R. Sant’Anna, E. Barreiro.

80) 2H-Benzimidazole 1,3-dioxide derivatives: A new family of water-soluble anti-trypanosomatid
2006
J. Med. Chem., 2006, 49, 3215–3220
M. Boiani, L. Boiani, A. Denicola, S. Torres de Ortiz, E. Serna, N. Vera de Bilbao, L. Sanabria, G. Yaluff, H. Nakayama, A. Rojas de Arias, C. Vega, M. Rolan, A. Gómez-Barrio, H. Cerecetto, M. González.

79) Pd(Thiosaccharinato)2.H2O, the First Thiosaccharinato Complex of a Platinum-Group Metal
2006
J. Coord. Chem., 2006, 59, 101–106
D. Gambino, M. González, H. Cerecetto, S. H. Tarulli, O. V. Quinzani, E. J: Baran.

78) Furoxan Derivatives as Cytotoxic Agents: Preliminary in vivo Antitumoral Activity Studies
2006
Pharmazie, 2006, 61, 54-59
G. Aguirre, M. Boiani, H. Cerecetto, M. Fernández, M. González, E. León, C. Pintos, S. Raymondo, C. Arredondo, J. P. Pacheco, M. A. Basombrío.

77) Review: Advances in the synthesis and recent therapeutic applications of 1,2,4-thiadiazole heterocycles
2006
Bioorg. Med. Chem., 2006, 14, 1644-1652
A. Castro, T. Castano, A. Encinas, W. Porcal, C. Gil.

76) ESR and Electrochemical Study of 5-Nitroindazole Derivatives with Antiprotozoal Activity
2006
Spectrochim. Acta A Mol. Biomol. Spectrosc., 2006, 63, 36-42
C. Olea-Azar, H. Cerecetto, A. Gerpe, M. González, V. J. Arán, C. Rigol, L. Opazo.

75) Review: Pharmacological Properties of Indazole and their N-oxides: Recent Developments
2005
Mini Rev. Med. Chem., 2005, 5, 869-878
H. Cerecetto, A. Gerpe, M. González, V. J. Arán, C. Ochoa.

74) Relationship Between Physicochemical Properties and Herbicidal Activity of 1,2,5-Oxadiazole N-Oxide Derivatives
2005
Molecules, 2005, 10, 1197-1208
L. A. Fernandez, M. R. Santo, M. Reta, L. Giacomelli, R. Cattana, J. J. Silber, M. Risso, H. Cerecetto, M. Gonzalez, C. Olea-Azar.

73) Novel Benzo[1,2-c]1,2,5-Oxadiazole N-Oxide Derivatives as Antichagasic Agents: Chemical and Biological Studies
2005
Letters Drugs Des. Dev., 2005, 2, 294-301
C. Olea-Azar, C. Rigol, F. Mendizábal, H. Cerecetto, R. Di Maio, M. González, W. Porcal, A. Morello, Y. Repetto, J. D. Maya.

72) 2-Imidazolone Derivatives Obtained as Unexpected Products Throughout Imidazole N3-Oxide Rearrangement
2005
Letters Org. Chem., 2005, 2, 501-506
H. Cerecetto, A. Gerpe, M. González, O. E. Piro, E. E. Castellano.

71) New Potent 5-Substituted Benzofuroxans as Inhibitors of Trypanosoma cruzi Growth. Quantitative Structure-Activity Relationship Studies
2005
Bioorg. Med. Chem., 2005, 13, 6336-6346
G. Aguirre, L. Boiani, M. Boiani, H. Cerecetto, R. Di Maio, M. González, W. Porcal, A. Denicola, O. E. Piro, E. E. Castellano, C. M. R. Sant’Anna, E. J. Barreiro.

70) Benzo[1,2-c]1,2,5-Oxadiazole N-oxide Derivatives as Potential Antitrypanosomal Drugs. Part III. Substituents-Clustering Methodology in the Search of New Active Compounds
2005
Bioorg. Med. Chem., 2005, 13, 6324-6335
G. Aguirre, L. Boiani, H. Cerecetto, R. Di Maio, M. González, W. Porcal, L. Thomson, V. Tórtora, A. Denicola, M. Möller.

69) Preparation of Phenazine N5,N10-Dioxides. Effects of Benzofuroxan Substituents in the Outcome of their Expansion Reaction with Phenolates
2005
J. Braz. Chem. Soc., 2005, 6, 1290-1296
H. Cerecetto, M. González, M. L. Lavaggi, W. Porcal.

68) Design, Synthesis and Biological Characterization of Novel Antiatherogenic Tocopherol Analogs-Nitric Oxide Donors
2005
Bioorg. Med. Chem., 2005, 13, 5787-5796
G. V. López, C. Batthyány, F. Blanco, H. Botti, A. Trostchansky, E. Migliaro, R. Radi, M. González, H. Cerecetto, H. Rubbo.

67) Chemoselective hydrolysis of the iminic moiety in salicylaldehyde semicarbazone promoted by ruthenium
2005
Inorg. Chem. Acta, 2005, 358, 3065-3074
M. Vieites, P. Buccino, L. Otero, M. González, O. E. Piro, R. Sánchez Delgado, M. Sant’Anna, E. Barreiro, H. Cerecetto, D. Gambino.

66) Synthesis and Biological Properties of New 5-Nitroindazole Derivatives
2005
Bioorg. Med. Chem., 2005, 13, 3197-3207
V.J. Arán, C. Ochoa, L. Boiani, P. Buccino, H. Cerecetto, A. Gerpe, M. González, D. Montero, J.J. Nogal, A. Gómez-Barrio, A. Azqueta, A. López de Ceraín, O.E. Piro, E.E. Castellano.

65) Novel Cu(II) Quinoxaline N1,N4-Dioxide Complexes as Selective Hypoxic Cytotoxins
2005
Eur. J. Med. Chem., 2005, 40, 473-480
M. H. Torre, D. Gambino, J. Araujo, H. Cerecetto, M. González, M. L. Lavaggi, A. Azqueta, A. López de Cerain, A. Monge Vega, U. Abram, A. J. Costa-Filho.

64) Phenazine 5,10-Dioxide Derivatives as Hypoxic Selective Cytotoxins
2005
J. Med. Chem., 2005, 48, 21-23
H. Cerecetto, M. González, M. L. Lavaggi, A. Azqueta, O. Ezpeleta, A. López de Cerain, A. Monge-Vega.

63) Review: Pharmacological properties of furoxans and benzofuroxans: recent developments
2005
Mini Rev. Med. Chem., 2005, 5, 57-71
H. Cerecetto, W. Porcal.

62) Vanadium(V) Complexes with Salicylaldehyde Semicarbazone Derivatives bearing in vitro Anti-tumor Activity.Crystal Structure of [VVO2(5-bromosalicylaldehyde semicarbazone)]
2005
J. Inorg. Biochem., 2005, 99, 443-451
P. Noblía, M. Vieites, B. Parajón-Costa, E. J. Baran, H. Cerecetto, M. González, P. Draper, O. E. Piro, E. E. Castellano, A. Azqueta, A. López de Ceráin, A. Monge-Vega, D. Gambino.

61) Review: Imidazole and Benzimidazole Derivatives as Chemotherapeutic Agents.
2005
Mini Rev. Med. Chem., 2005, 5, 409-24
M. Boiani, M. González.

60) Electrochemical and ESR Study of 5-Nitrofuryl containing Thiosemicarbazones Antiprotozoal Drugs
2005
Spectrochim. Acta A Mol. Biomol. Spectrosc., 2005, 61, 2933-2938
C. Rigol, C. Olea-Azar, F. Mendizábal, L. Otero, D. Gambino, M. González, H. Cerecetto.

59) Tautomerism and Reactivity in Heterocycles N-Oxides: A Spectroscopic and Theoretical Study of Benzimidazole N-Oxide Derivatives (N-Hydroxybenzimidazoles)
2004
J. Phys. Chem. Part A, 2004, 108, 11241-11248
M. Boiani, H. Cerecetto, M. González, O. E. Piro, E. E. Castellano.

58) In vitro activity and mechanism of action against the protozoan parasite Trypanosoma cruzi of 5-nitrofuryl containing thiosemicarbazones
2004
Bioorg. Med. Chem., 2004, 12, 4885-4893
G. Aguirre, L. Boiani, H. Cerecetto, M. Fernández, M. González, A. Denicola, L. Otero, D. Gambino, C. Rigol, C. Olea-Azar, M. Faúndez.

57) New Synthetic Approach for Preparation of Imidazole N3-Oxide
2004
Synthesis, 2004, 16, 2678-2684
H. Cerecetto, A. Gerpe, M. González, Y. Fernández Sainz, O. E. Piro, E. E. Castellano.

56) Cytotoxicity of Furoxans: Quantitative Structure-Activity Relationships Study
2004
Farmaco, 2004, 59, 405-412
M. Boiani, H. Cerecetto, M. González.

55) Quinoxaline N,N’-Dioxide Derivatives and Related Compounds as Growth Inhibitors of Trypanosoma cruzi. Structure-Activity Relationships
2004
Bioorg. Med. Chem. Letters, 2004, 14, 3835-3839
G. Aguirre, H. Cerecetto, R. Di Maio, M. González, M.E. Montoya Alfaro, A. Jaso, B. Zarranz, M.A.l Ortega, I. Aldana, A. Monge-Vega.

54) Design, Synthesis and Biological Evaluation of New Potent 5-Nitrofuryl Derivatives as Anti-Trypanosoma Cruzi Agents. Studies of Trypanothione Binding Site of Trypanothione Reductase as Target for Rational Design
2004
Eur. J. Med. Chem., 2004, 39, 421-431
G. Aguirre, E. Cabrera, H. Cerecetto, R. Di Maio, M. González, G. Seoane, A. Duffaut, A. Denicola, M. J. Gil, V. Martínez-Merino.

53) 1,2,4-Triazine N-oxide Derivatives: Studies as Potential Hypoxic Cytotoxins. Part III
2004
Archiv. Pharmazie, 2004, 337, 271-280
H. Cerecetto, M. González, M. Risso, P. Saenz, C. Olea-Azar, A. M. Bruno, A. Azqueta, A. López de Ceráin, A. Monge.

52) Novel Antiprotozoal Products: Imidazole and Benzimidazole N-Oxide Derivatives and Related Compounds
2004
Archiv. Pharmazie, 2004, 337, 259-270
G. Aguirre, M. Boiani, H. Cerecetto, A. Gerpe, M. González, Y. Fernández Sainz, A. Denicola, C. Ochoa de Ocáriz, J. J. Nogal, D. Montero, J. A. Escario.

51) Ruthenium (II) Nitrofurylsemicarbazone Complexes: New DNA Binding Agents
2004
Eur. J. Med. Chem., 2004, 39, 377-382
E. Cabrera, H. Cerecetto, M. González, D. Gambino, P. Noblia, L. Otero, B. Parajón-Costa, A. Anzillotti, R. Sánchez-Delgado, A. Azqueta, A. López de Ceráin, A. Monge.

50) Mass Spectrometry of 1,2,5-Oxadiazole N-Oxide Derivatives. Use of Deuterated Analogues in Fragmentation Pattern Studies
2004
J. Braz. Chem. Soc., 2004, 15, 232-240
H. Cerecetto, M. González, G. Seoane, C. Stanko, O. E. Piro, E. E. Castellano.

49) 1,2,4-Triazine N-Oxide Derivatives: Studies as Potential Hypoxic Cytotoxins. Part II
2004
Archiv. Pharmazie, 2004, 337, 247-258
H. Cerecetto, M. González, S. Onetto, P. Saenz, O. Ezpeleta, A. López de Ceráin, A. Monge-Vega.

48) New Vanadium(V) Complexes with Salicylaldehydesemicarbazone Derivatives: Synthesis, Characterization and Insulinomimetic Activity. Crystal Structure of [VvO2 (Salicylaldehydesemicarbazone)]
2004
Eur. J. Inorg. Chem., 2004, 2, 322-328
P. Noblia, D. Gambino, L. Otero, E. J. Baran, P. Draper, H. Cerecetto, M. González, O. E. Piro, E. E. Castellano, H. Sakurai.

47) ESR and Spin Trapping Studies of Two New Potential Antitrypanosomal Drugs
2003
J. Chil. Chem. Soc., 2003, 48, 77-79
C. Olea-Azar, C. Rigol, L. Opazo, A. Morello, J. D. Maya, Y. Repetto, G. Aguirre, H. Cerecetto, R. Di Maio, M. González, W. Porcal.

46) ESR Spin Trapping Studies of Free Radicals Generated from Nitrofuran Derivatives Analogues of Nifurtimox by Electrochemical and Trypanosoma cruzi Reduction
2003
Free Rad. Res., 2003, 37, 993-1001
C. Olea-Azar, C. Rigol, F. Mendizabal, A. Morello, J.D. Maya, C. Moncada, E. Cabrera, R. Di Maio, M. González, H. Cerecetto.

45) Electrochemical and Microsomal Production of Free Radicals from 1,2,5-Oxadiazole N-Oxide as Potential Antiprotozoal Drugs
2003
Spectrochim. Acta Part A, 2003, 59, 69-74
C. Olea-Azar, C. Rigol, F. Mendizabal, R. Briones, H. Cerecetto, R. Di Maio, M. González, W. Porcal, M. Risso.

44) Synthesis and Characterization of New Ruthenium Complexes with Active Ligands against Chagas’ Disease
2003
Inorg. Chim. Acta, 2003, 344, 85-94
L. Otero, P. Noblia, D. Gambino, H. Cerecetto, M. González, R. Di Maio, J. Ellena, O.E. Piro.

43) New Re(V) Nitrofuryl Semicarbazone Complexes. Crystal Structure of [ReOCl2(PPh3)(3-(5-nitrofuryl)acroleine semicarbazone]
2003
Zeitschrift für Anorganische und Allgemeine Chemie, 2003, 629, 1033-1038
L. Otero, P. Noblia, D. Gambino, H. Cerecetto, M. González, R. Sánchez Delgado, E. E. Castellano, O. E. Piro.

42) An Effective One-pot Synthesis of 5-Substituted Tetronic Acids
2003
J. Org. Chem., 2003, 68, 3363-3365
D. Tejedor Aragón, G.V. López, F. García-Tellado, J.J. Marrero-Tellado, P. de Armas, D. Terrero.

41) Solvent Effect In The Wittig Reaction Under Boden´s Conditions
2003
Synthetic Commun., 2003, 33, 2187-2196
E.M. Pandolfi, G.V. López, E. Días, G. Seoane.

40) Benzo[1,2-c]1,2,5-oxadiazole N-Oxide Derivatives as Potential Antitrypanosomal Drugs. Structure-Activity Relationships. Part II
2002
Archiv. Pharmazie, 2002, 335, 15-21
G. Aguirre, H. Cerecetto, R. Di Maio, M. González, W. Porcal, G. Seoane, A. Denicola, M.A. Ortega, I. Aldana, A. Monge-Vega.

39) Review: Chemotherapy of Chagas’ Disease: Status and New Developments
2002
Curr. Topics Med. Chem., 2002, 2, 1185-1213
H. Cerecetto, M. González.

38) Computer Assisted Design of Potentially Active Anti-trypanosomal Compounds
2002
J. Mol. Struct. THEOCHEM, 2002, 584, 95-105
M. Paulino, F. Iribarne, M. Hansz, M. Vega, G. Seoane, H. Cerecetto, R. Di Maio, I. Caracelli, J. Zukerman-Schpector, C. Olea, A. O. M. Stoppani, M. Berriman, A. H. Fairlamb, O. Tapia.

37) Characterization of [Re(V)O(Tetramethylthiourea)4](PF6)3 in Solution: Electrochemical, NMR and Ligand Substitution Studies
2002
J. Coord. Chem., 2002, 55, 1441-1453
D. Gambino, B. Parajón-Costa, H. Cerecetto, M. González, E. Kremer, E.J. Baran.

36) 1,2,5-Oxadiazole N-Oxide Derivatives as Potential Anti-cancer Agents: Synthesis and Biological Evaluation. Part IV
2001
Eur. J. Med. Chem., 2001, 36, 771-782
M. Boiani, H. Cerecetto, M. González, M. Risso, C. Olea-Azar, O. Ezpeleta, A. López de Ceráin, A. Monge.

35) Review: N-Oxides as Hypoxia Selective Cytotoxins
2001
Mini Rev. Med. Chem., 2001, 1, 219-231
H. Cerecetto, M. González.

34) CoMFA-SIMCA Model for Antichagasic Nitrofurazone Derivatives
2001
Bioorg. Med. Chem., 2001, 9, 1025-1030
V. Martínez-Merino, H. Cerecetto.

33) 1,2,4-Triazine N-oxide and Di-N-oxide Derivatives. Synthesis and Evaluation as Hypoxia Selective Cytotoxins
2001
Med. Chem. Res., 2001, 10, 328-337
H. Cerecetto, M.González, S. Onetto, M. Risso, P. Saenz, G. Seoane, A. Monge, A. López de Ceráin, O. Ezpeleta, C. Olea-Azar, A. M. Bruno.

32) Synthesis and Biological Evaluation of 1,2,5-Oxadiazole N-Oxide Derivatives as Potential Hypoxic Cytotoxins and DNA-Binders
2000
Archiv. Pharmazie, 2000, 333, 387-393
H. Cerecetto, M. González, M. Risso, G. Seoane, A. López de Ceráin, O. Ezpeleta, A. Monge, L. Suescun, A. Mombrú, A. M. Bruno.

31) New Thiadiazine Derivatives with Activity against Trypanosoma cruzi Amastigotes
2001
Folia Parasitol., 2001, 48, 105-108
S. Muelas, R. Di Maio, H. Cerecetto, G. Seoane, C. Ochoa, J. A. Escario, A. Gómez Barrio.

30) Marchantin M trimethylethe
2000
Acta Crystallographica Section C, 2000, C56, 1374-1376
A.W. Mombrú, L. Suescun, E. Pandolfi, G.A. Seoane, G.V. López, R.S. Mariezcurrena.

29) Total Synthesis of Marchantinquinone
2000
Synthesis, 2000, 1403-1408
G.V. López, E.M. Pandolfi, G.A. Seoane.

28) Synthesis and Herbicidal Activity of N-oxide Derivatives
2000
J. Agric. Food Chem., 2000, 48, 2995-3002
H. Cerecetto, E. Dias, R. Di Maio, M. González, S. Pacce, P. Saenz, G. Seoane, L. Suescun, A. Mombrú, G. Fernández, M. Lema, J. Villalba.

27) Synthesis and Anti-trypanosomal Evaluation of E-isomers of 5-Nitro-2-furaldehyde and 5-Nitrothiophene-2-carboxaldehyde Semicarbazones Derivatives. Structure-activity Relationships
2000
Eur. J. Med. Chem., 2000, 35, 343-350
H. Cerecetto, R. Di Maio, M. González, M. Risso, G. Sagrera, G. Seoane, A. Denicola, G. Peluffo, C. Quijano, A. O. M. Stoppani, M. Paulino, C. Olea-Azar, M. A. Basombrio.

26) Actividad lipolítica de nuevos agonistas adrenérgicos ß3 en adipocitos de rata y humanos: Posibles agentes para la futura terapia de la obesidad
1999
Anales de la Real Academia de Farmacia, 1999, 65, 627-642
Aldana, I., Monge, A., Cerecetto, H., Rivero, A., Aguado, M., Margareto, J., Alfredo Martínez, J., Caignard, D.H.

25) Synthesis and Antichagasic Properties of New 1,2,6-Thiadiazin-3,5-dione 1,1-Dioxides and Related Compounds
1999
Arzneim.-Forsch./Drug Res., 1999, 49, 759-763
R Di Maio, H. Cerecetto, G. Seoane, C. Ochoa, V. J. Arán, E. Pérez, A. Gómez Barrio, S. Muelas, A. R. Martínez.

24) 1,2,5-Oxadiazole N-oxide Derivatives and Related Compounds as Potential Antitrypanosomal Drugs. Structure-Activity Relationships
1999
J. Med. Chem., 1999, 42, 1941-1950
H. Cerecetto, R Di Maio, M. González, M. Risso, P. Saenz, G. Seoane, A. Denicola, G. Peluffo, C. Quijano, C. Olea-Azar.

23) Aproximación a la Síntesis de Constituyentes de Briofitas
1998
Información Tecnológica, 1998, 9, 11-17
G. Sagrera G., G.V. López, E. Pandolfi, G. Seoane, T. Eicher.

22) Electron Spin Resonance and Cyclic Voltammetry Studies of Nitrofurane and Nitrothiophene Analogues of Nifurtimox
1998
Spectrosc. Letters, 1998, 31, 849-857
C. Olea-Azar, A. M. Atria, R. Di Maio, G. Seoane, H. Cerecetto.

21) Cyclic Voltammetry and Electron Paramagnetic Resonance Studies of Some Analogues of Nifurtimox
1998
Spectrosc. Letters, 1998, 31, 99-109
C. Olea-Azar, A. M. Atria, F. Mendizabal, R. Di Maio, G. Seoane, H. Cerecetto.

20) Synthesis and Anti-Trypanosomal Activity of Novel 5-Nitro-2-furaldehyde and 5-Nitrothiophene-2-carboxaldehyde Semicarbazones Derivatives
1998
Farmaco, 1998, 53, 89-94
H. Cerecetto, R. Di Maio, G. Ibarruri, G. Seoane, A. Denicola, C. Quijano, G. Peluffo, M. Paulino.

19) Synthesis and Biological Evaluation of 1,2,5-Oxadiazole N-Oxide Derivatives as Hypoxia-Selective Cytotoxins
1998
Pharmazie, 1998, 53, 758-764
A. Monge, A. López de Ceráin, O. Ezpeleta, H. Cerecetto, E. Dias, R. Di Maio, M. González, S. Onetto, G. Seoane, L. Suescun, R. Mariezcurrena.

18) 1,2,5-Oxadiazole N-Oxide Derivatives as Hypoxia-Selective Cytotoxins. Structure-Activity Relationships
1998
Pharmazie, 1998, 53, 698-702
A. Monge, A. López de Ceráin, O. Ezpeleta, H. Cerecetto, E. Dias, R. Di Maio, M. González, S. Onetto, M. Risso, G. Seoane, F. Zinola, C. Olea-Azar.

17) Preparation of Enamines from the Condensation of Glycine Esters with Nitro-heterocyclic Aldehydes
1997
Heterocycles, 1997, 45, 2023-2031
H. Cerecetto, R. Di Maio, M. González, G. Seoane.

16) Comparative Molecular Field Analysis (CoMFA) on [6]+[6] fused Pyrazines with Nematocide Properties
1997
QSAR, 1997, 16, 372-376
A.Martínez, C.Ochoa, J.Rodríguez, M.Rodríguez, A.Castro, M.González, M.Martínez.

15) Fármacos Biorreductivos: ¿Potenciales Quimioterápicos en Cáncer?
1997
Revista de la Asociación de Química y Farmacia del Uruguay, 1997, 20, 34
H.Cerecetto, M.González.

14) 4-Cyano-2-oxo-1,2,4-oxadiazolo[2,3-a]quinoxaline-5-N-oxides. New Synthetic Method and Reaction with Alcohols. Potential Cytotoxic Activity.
1996
J. Heterocyclic Chem., 1996, 33, 1-7
F. J. Martínez-Crespo, J. A. Palop, Y. Sainz, S. Narro, V. Senador, M. González, A. López de Ceráin, A. Monge, E. Hamilton, A. J. Baker.

13) A New Analogue of Nifurtimox
1996
Acta Crystallographica Section C, 1996, C52, 1281-1282
I. Caracelli, F. M. L. G. Stamato, B. Mester, M. Paulino, H. Cerecetto.

12) Synthesis of New Oxazolidine, Oxazolidin-2-one and Perhydro-1,4-oxazine Derivatives of Arylethanolamine as Potential ß3-Adrenoceptor Agonists
1995
J. Heterocyclic Chem., 1995, 32, 1429-1439
A. Monge, I. Aldana, H. Cerecetto, A. Rivero.

11) New Perhydro-1,4-oxazine Derivatives of Arylethanolamines with ß3-Adrenoceptor Agonist Activity
1995
Pharmazie, 1995, 50, 768-769
A. Monge, I. Aldana, H. Cerecetto, A. Rivero, A. del Barrio, R. Pérez, M. Portillo, A. Martínez.

10) New Hypoxia-Selective Cytotoxines Derived from Quinoxaline 1,4-Dioxides.
1995
J. Heterocyclic Chem., 1995, 32, 1213-1217
F. J. Martínez-Crespo, J. A. Palop, Y. Sainz, S. Narro, V. Senador, M. González, A. López de Ceráin, A. Monge, E. Hamilton, A. J. Baker.

9) Hypoxia-Selective Agents Derived from 2-Quinoxalinecarbonitrile 1,4- Di-N-oxides.2.
1995
J. Med. Chem., 1995, 38, 4488-4494
A. Monge, F. J. Martínez-Crespo, A. López de Ceráin, J. A. Palop, S. Narro, V. Senador, A. Marín, Y. Sainz, M. González, E. Hamilton, A. J. Baker.

8) Hypoxia-Selective Agents Derived from Quinoxaline 1,4-Di-N-oxides.
1995
J. Med. Chem., 1995, 38, 1786-1792
F. J. Martínez-Crespo, J. A. Palop, Y. Sainz, S. Narro, V. Senador, M. González, A. López de Ceráin, A. Monge, E. Hamilton, A. J. Baker.

7) 3-Amino-2-Quinoxalinecarbonitrile. New Fused Quinoxaline with Potential Cytotoxic Activity.
1994
J. Heterocyclic Chem., 1994, 31, 1135-1139
A. Monge, J. A. Palop, A. Piñol, F. J. Martínez-Crespo, S. Narro, M. González, Y. Sainz, A. López de Ceráin, E. Hamilton, A. J. Baker.

6) Formal Potentials Of New Analogues Of Nifurtimox: Relationship to Activity
1992
Farmaco, 1992, 47, 1207-1213
H.Cerecetto, B.Mester, S.Onetto, G.Seoane, M.González, F.Zinola.

 


Publicaciones en enseñanza

5) Uso de Simulaciones Tridimensionales en Formato Electrónico en Cursos de Química Orgánica para Licenciaturas de Biociencias
2005
Anuario Latinoamericano de Educación en Química, 2005, 80-86
P. Buccino, M. Boiani, H. Cerecetto, A. Gerpe, M. González, M. L. Lavaggi, G. V. López, W. Porcal, X. Otegui, M. Míguez, J. L. López Pérez.

4) Molecular Modeling as Didactic Tool for the First Course of Organic Chemistry
2004
Revista Educación Química, 2004, 15, 349-352
M. Boiani, P. Buccino, H. Cerecetto, M. González, V. López, P. Saenz, G. Seoane, S. Loureiro, M. Míguez, X. Otegui.

3) Aplicación de Talleres de Investigación en el Curso Práctico de Química Orgánica
2001
Anuario Latinoamericano de Educación en Química, 2001, 83-122
G. Seoane, H. Cerecetto, E. Pandolfi, M. González, R. Di Maio, M. Brovetto, V. López, P. Saenz, P. Buccino, E. Dias.

2) Percepción Estudiantil de Cursos de Laboratorio de Química Orgánica. Tradicionales y con Mini-Proyectos de Investigación
2001
Anuario Latinoamericano de Educación en Química, 2001, 123-128
G. Seoane, H. Cerecetto, E. Pandolfi, M. González, R. Di Maio, M. Brovetto, V. López, P. Saenz, P. Buccino, E. Dias.

1) Uso del Video en el Curso Práctico de Química Orgánica. Una Experiencia Nueva en Nuestro Laboratorio
1991
Anuario Latinoamericano de Educación en Química, 1991, 149-152
G. Seoane, H. Cerecetto, S. Onetto, C. Volonterio.


Patentes

1) Título: Derivados de 1,4-Dióxido de Quinoxalina, Procedimiento de Preparación y de Utilización.
1995
País prioridad: España
Nº: P9500076
Autores Intelectuales: A. Monge, J. A. Palop, F. J. Martínez-Crespo, Y. Sainz, S. Narro, V. Senador, M. González, A. López de Ceráin, E. Hamilton, A. J. Baker.

2) Título: Derivados de 5-Etenilbenzofuroxano, Procedimiento de Preparación y Utilización
2003
País prioridad: Uruguay
Nº: UR 28019
Autores Intelectuales: H. Cerecetto, M. González, R. Di Maio, W. Porcal, A. Denicola.

3) Título: Análogos de Tocoferol Dadores de Óxido Nítrico
2004
País prioridad: Uruguay
Nº: UR 28445
Autores Intelectuales: M. González, V. López, H. Cerecetto, C. Batthyány, H. Rubbo, R. Radi.

4) Título: Complejos Metálicos de Paladio y Platino con Tiosemicarbazonas Derivadas de 5-Nitrofurano, Procedimiento de Preparación y Utilización
2004
País prioridad: Uruguay
Nº: UR 28563
Autores Intelectuales: M. González, H. Cerecetto, D. Gambino, L. Otero.

5) Título: Derivados de 1,3-Dióxido de Benzimidazol, Procedimiento de Preparación y Utilización
2005
País prioridad: Uruguay
Nº: UR 29076
Autores Intelectuales: M. González, H. Cerecetto, M. Boiani, A. Merlino.